Endocrine Abstracts

Introduction: T1DM is caused by immune mediated destruction of pancreatic β-cells, leading to partial, or absolute insulin deficiency.The most frequent age of onset is 12 years. IGF-1 is a polypeptide with 70 amino acids and its chemical structure is similar to insulin. IGF-1 is associated with early development and has anabolic effect in adults. IGF-1 regulates many physiological functions, including glucose metabolism, cell survival and proliferation.<p class="abste...